Supportive Oligonucleotide Therapy (SOT)


Molecular medicine continues to grow in popularity as an increasing number of hard to treat diseases respond to these types of therapies. Multiple FDA approved molecular SOT treatments are available with impressive results in conditions that have otherwise been untreatable including Duchenne's Muscular Dystrophy and Spinal Muscular Atrophy.

SOT, otherwise known as Supportive Oligonucleotide Therapy or Antisense is a breakthrough therapy that utilizes molecular building blocks (mRNA) found naturally in the patient’s own body.  It is not a drug and there is no gene manipulation.  SOT targets the gene-replication sequences preventing the pathogen’s replication and effectively eliminating the infection from the body. SOT is not an immune treatment. It does not alter the immune system. Side effects are minimal since it is made specifically for and therefore highly compatible with the patient. This technology has a 98% specificity to the target genes such as the Lyme spirochete and does not interfere with any other human cells. 

SOT has already been used efficaciously in many diseases including HIV and multiple forms of cancer.  It has also been proven to be effective in various infectious diseases such as Lyme, HSV1, HSV2, CMV, HSV-6, Epstein-Barr (EBV) and others.  Over 90% of the world’s population has been infected with one of these stealth or dormant infections, Epstein-Barr being one of the most common. Although some people never develop symptoms, many will suffer with generalized or non-descript immune symptoms that cause debilitating conditions including chronic fatigue and fibromyalgia. Stealth infections are difficult for the body to defend against and equally as difficult for medications to target.  As a result, countless people live with these infections for decades. Many will remain sick without the use of molecular medicine (SOT) in spite of attempting traditional medical treatments.


At BodyScience we offer two SOT molecular treatment options, SOT and SOT Plus. An example of a patient who would benefit from SOT therapy is anyone with non-complicated Lyme disease or other non-complicated infections such as HSV or HPV. By comparison, SOT Plus provides additional support needed by individuals with more complex symptomatology; those with persistent or complex infections affecting the nervous and immune systems.  An example is someone who has been diagnosed with Lyme disease that has progressed into the nervous system exhibiting features of Motor Neuron dysfunction.

The SOT Process


A small amount of blood is drawn in our office to obtain the circulating pathogen.  It is sent to the laboratory where the pathogen is genetically deconstructed.  The sequences that control reproduction are identified and used to produce the specific Supportive Oligonucleotide Therapy (SOT).  The completed SOT is shipped to our center and administered by IV infusion which takes an hour or less.  IV antihistamines and low dose steroids are given immediately prior to SOT administration in order to lessen the already rare chance of an allergic reaction and decrease the chance of SOT leakage.  SOT may be repeated up to three times per year if needed.  The main side effects of SOT are detox or "Herx" reactions (fatigue, body aches and headaches). The SOT Plus program includes peptide therapies as well as IV light therapy and IV antioxidant support needed by those with chronic, severe disease.

Chemistry of Oligonucleotide Therapeutics 101

SOT can be used for many conditions including:

Lyme - Related



B. mayonii 

B. burgdorferi 

B. garinii 

B. bissettii 

B. bavariensis 

B. valaisiana 

B. afzelii 

B. finlandensis 

B. recurrentis 

B. genomospecies 

B. hermsii 

B. lusitaniae 

B. sinica 

Candidatus B. tachyglossi 

B. miyamotoi 


 B. henselae 

 B. bacilliformis 

 B. vinsonii 

 B. quintana 

 B. elizabethae 



B. microti 

B. bigemina 

B. divergens 

B. duncani 

B. bovis

IV light therapy

Virus - Related


HHV1/HSV1 — (Human Simplex Virus-Oral-Facial)

HHV2/HSV2 — (Human Simplex Virus-Genital)

HHV6 (A & B) — (Human Herpes Virus 6)

CMV — (Cytomegalovirus)

Coxsackie (Type A & B)

VZV — Varicella-zoster (shingles)

EBV — (Epstein Barr)

HPV (16/18) — Human papillomavirus

HPV (6/11) — Human papillomavirus

HBV — (Hepatitis B)

HCV — (Hepatitis C)

HIV — (Human Immunodeficiency Virus)-AIDS

HTLV1— (Human T-cell Lymphotropic Virus)