“Advanced ALS Care Designed for Real Progress and Real Hope.”
BodyScience is a dedicated ALS clinic using the most advanced diagnostic and therapeutic technologies available today. Our team specializes exclusively in ALS, combining precision biomarkers, cutting‑edge immune and metabolic analysis, and innovative treatment protocols to slow progression and improve quality of life. We provide comprehensive, science‑driven care tailored to each patient’s unique biology—delivering a new standard of hope, clarity, and forward‑thinking ALS treatment.
Exosomes
Exosomes: A cell-to-cell transit system in the human body with pleiotropic functions.
Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They are mediators of near and long-distance intercellular communication in health and disease and affect various aspects of cell biology.
Abstract
The study of extracellular vesicles (EVs) has the potential to identify unknown cellular and molecular mechanisms in intercellular communication and in organ homeostasis and disease. Exosomes, with an average diameter of ~100 nanometers, are a subset of EVs. The biogenesis of exosomes involves their origin in endosomes, and subsequent interactions with other intracellular vesicles and organelles generate the final content of the exosomes. Their diverse constituents include nucleic acids, proteins, lipids, amino acids, and metabolites, which can reflect their cell of origin. In various diseases, exosomes offer a window into altered cellular or tissue states, and their detection in biological fluids potentially offers a multicomponent diagnostic readout. The efficient exchange of cellular components through exosomes can inform their applied use in designing exosome-based therapeutics.
Reference: science.org
